CGP52411 (Standard)

Overview

CGP52411 (Standard) is the analytical standard of CGP52411 ( HY-103442 ). This product is intended for research and analytical applications. CGP52411 (DAPH) is a high selective, potent, orally active and ATP-competitive EGFR inhibitor with an IC 50 of 0.3 μM. CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells, and dramatic inhibits and reverses the formation of β-amyloid (Aβ42) fibril aggregates associated with Alzheimer's disease.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Amyloid-β

Product Information

• Catalog No.: HY-103442R
• CAS No.: 145915-58-8
• Molecular Formula: C20H15N3O2
• Molecular Weight: 329.35
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source