CI-966 hydrochloride (Standard)

Overview

CI-966 hydrochloride (Standard) is the analytical standard of CI-966 hydrochloride ( HY-103534 ). This product is intended for research and analytical applications. CI-966 hydrochloride is a potent, selective, orally active and brain-penetrant inhibitor of the GABA transporter GAT-1, with IC 50 s of 0.26 μM and 1.2 μM for hGAT-1, rGAT-1, respectively. CI-966 hydrochloride shows more than 200-fold selectivity over GAT-2, GAT-3, and BGT-3. CI-966 hydrochloride exhibits anticonvulsant and neuroprotective activities.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > GABA Receptor

Product Information

• Catalog No.: HY-103534R
• CAS No.: 110283-66-4
• Molecular Formula: C23H22ClF6NO3
• Molecular Weight: 509.87
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source