IDH-305 (Standard)

Overview

IDH-305 (Standard) is the analytical standard of IDH-305 ( HY-104036 ). This product is intended for research and analytical applications. IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor that targets IDH1 (R132) mutation. IDH-305 exhibits greater than 200 fold selectivity for mutant IDH1 isoforms vs. WT (IC 50 = 27 nM (IDH1R132H), 28 nM (IDH1R132C), 6.14 µM (IDH1WT)).

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Isocitrate Dehydrogenase (IDH)

Product Information

• Catalog No.: HY-104036R
• CAS No.: 1628805-46-8
• Molecular Formula: C23H22F4N6O2
• Molecular Weight: 490.45
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source