TAK-715 (Standard)

Overview

TAK-715 (Standard) is the analytical standard of TAK-715 ( HY-10456 ). This product is intended for research and analytical applications. TAK-715 is an orally active and potent p38 MAPK inhibitor with IC 50 s of 7.1 nM, 200 nM for p38α and p38β , respectively. TAK-715 inhibits casein kinase I (CK1δ/ε) to regulate activation of Wnt/β-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > Casein Kinase | Products > Signaling Pathways > Wnt

Product Information

• Catalog No.: HY-10456R
• CAS No.: 303162-79-0
• Molecular Formula: C24H21N3OS
• Molecular Weight: 399.51
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source