THIQ (Standard)

Overview

THIQ (Standard) is the analytical standard of THIQ ( HY-10624 ). This product is intended for research and analytical applications. THIQ is the first selective agonist of the melanocortin-4 receptor ( MC4R ), with high affinity and potency for hMC4R (IC 50 =1.2 nM, EC 50 =2.1 nM) and rMC4R (IC 50 =0.6 nM, EC 50 =2.9 nM). THIQ maintains low potency at MC1R , MC3R and MC5R . THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Melanocortin Receptor

Product Information

• Catalog No.: HY-10624R
• CAS No.: 312637-48-2
• Molecular Formula: C33H41ClN6O2
• Molecular Weight: 589.17
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source