Antibiotic MX 2 is an orally active antibiotic that can cross the blood-brain barrier. Antibiotic MX 2 inhibits the growth of drug-sensitive and multidrug-resistant tumor cells, prolongs the survival of tumor-bearing mice, induces single-strand and double-strand DNA breaks, suppresses colony formation of fresh human-derived tumor cells, and overcomes multidrug resistance mediated by P-glycoprotein . Antibiotic MX 2 can be used in research related to L1210 leukemia, Lewis lung cancer , colon adenocarcinoma type 26 and type 38, gastric adenocarcinoma, non-small cell lung cancer , mammary adenocarcinoma, drug-resistant P388 leukemia, renal cancer , melanoma, ovarian cancer , breast cancer , small cell lung cancer , and colorectal cancer .
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