Carvotroline hydrochloride

Overview

Carvotroline hydrochloride is an antipsychotic agent and 5-HT 2 receptor antagonist, with a K i value of 211 nM for the 5-HT 2 receptor. Carvotroline hydrochloride modulates the activity of the stress-related hypothalamic-pituitary-adrenal axis. Carvotroline hydrochloride exerts a stronger blocking effect on Apomorphine ( HY-12723 )-induced climbing behavior than on Apomorphine -induced stereotyped behavior. Carvotroline hydrochloride inhibits conditioned avoidance responses in rats and monkeys without inducing catalepsy. Carvotroline hydrochloride can be used in studies related to schizophrenia.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Schizophrenia | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-106898A
• CAS No.: 136777-43-0
• Molecular Formula: C18H19ClFN3
• Molecular Weight: 331.81
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source