JNJ-10229570 (Standard)

Overview

JNJ-10229570 (Standard) is the analytical standard of JNJ-10229570 ( HY-107139 ). This product is intended for research and analytical applications. JNJ-10229570 is an antagonist of melanocortin receptor 1 ( MC1R ) and melanocortin receptor 5 ( MC5R ), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R , with IC 50 values of 270 nM and 200 nM, respectively.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Melanocortin Receptor

Product Information

• Catalog No.: HY-107139R
• CAS No.: 524923-88-4
• Molecular Formula: C22H19N3O2S
• Molecular Weight: 389.47
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source