Ro 5212773

Overview

Ro 5212773 (EPPTB) is a potent and selective trace amine-associated receptor 1 (TAAR1) antagonist ( K i =0.9 nM for mouse TAAR1), with no significant effects on other TAARs. TAAR1 is a G protein-coupled receptor (GPCR) that is nonselectively activated by endogenous metabolites of amino acids .

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Trace Amine-associated Receptor (TAAR)

Product Information

• Catalog No.: HY-110098
• CAS No.: 1110781-88-8
• Molecular Formula: C20H21F3N2O2
• Molecular Weight: 378.39
• Purity: 99.85%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.61 mM); Clear solution
• Availability: In-stock

Source

Original product source