PD-166793 (Standard)

Overview

PD-166793 (Standard) is the analytical standard of PD-166793 ( HY-107428 ). This product is intended for research and analytical applications. PD-166793 is a potent, selective, orally active and wide-broad spectrum inhibitor of MMP , exhibiting nanomolar potency against MMP-2 , MMP-3 and MMP-13 (IC 50 =4, 7, and 8 nM, respectively) and micromolar potency vs MMP-1 , -7 and -9 (IC 50 =6.0, 7.2, and 7.9 μM, respectively). PD-166793 can attenuate left ventricular remodeling and dysfunction in a rat model of progressive heart failure.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-107428R
• CAS No.: 199850-67-4
• Molecular Formula: C17H18BrNO4S
• Molecular Weight: 412.30
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source