TC-E 5003 (Standard)

Overview

TC-E 5003 (Standard) is the analytical standard of TC-E 5003 ( HY-107574 ). This product is intended for research and analytical applications. TC-E 5003 is a selective protein arginine methyltransferase 1 ( PRMT1 ) inhibitor with an IC 50 of 1.5 µM against hPRMT1. TC-E 5003 modulates the lipopolysaccharide (LPS) ( HY-D1056 )-induced AP-1 and NF-κB signaling pathways with anti-inflammatory properties. TC-E 5003 also upregulates the expression of Ucp1 and Fgf21, activates protein K i nase A signaling and lipolysis in primary subcutaneous adipocytes from both mouse and humans. TC-E 5003 is promising for research of obesity and associated metabolic disorders, oxidative stress, inflammation and cancers.

Application

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Product Information

• Catalog No.: HY-107574R
• CAS No.: 17328-16-4
• Molecular Formula: C16H14Cl2N2O4S
• Molecular Weight: 401.26
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source