YM-244769 hydrochloride (Standard)

Overview

YM-244769 hydrochloride (Standard) is the analytical standard of YM-244769 (hydrochloride) ( HY-107659 ). This product is intended for research and analytical applications. YM-244769 hydrochloride is a potent, selective and orally active Na+/Ca2+ exchanger (NCX) inhibitor. YM-244769 hydrochloride preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2+ entry mode), with IC 50 s of 18 nM and 50 nM, respectively. YM-244769 hydrochloride efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage. YM-244769 hydrochloride can also increase urine volume and urinary excretion of electrolytes in mice.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Na+/Ca2+ Exchanger

Product Information

• Catalog No.: HY-107659R
• CAS No.: 837424-39-2
• Molecular Formula: C26H23ClFN3O3
• Molecular Weight: 479.93
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source