LLY-283 (Standard) is the analytical standard of LLY-283 ( HY-107777 ). This product is intended for research and analytical applications. LLY-283 , a chemical probe, is a potent, selective and oral protein arginine methyltransferase 5 ( PRMT5 ) inhibitor, with an IC 50 of 22 nM and a K d of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity.
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