PIK-75 (Standard)

Overview

PIK-75 (Standard) is the analytical standard of PIK-75 ( HY-107834 ). This product is intended for research and analytical applications. PIK-75 is a reversible DNA-PK and p110α-selective inhibitor, which inhibits DNA-PK , p110α and p110γ with IC 50 s of 2, 5.8 and 76 nM, respectively. PIK-75 inhibits p110α >200-fold more potently than p110β (IC 50 =1.3 μM). PIK-75 induces apoptosis .

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > DNA-PK | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-107834R
• CAS No.: 372196-67-3
• Molecular Formula: C16H14BrN5O4S
• Molecular Weight: 452.28
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source