Facinicline hydrochloride (Standard) is the analytical standard of Facinicline (hydrochloride) ( HY-108057A ). This product is intended for research and analytical applications. Facinicline hydrochloride (RG3487 hydrochloride) is an orally active nicotinic α7 receptor partial agonist, with a K i of 6 nM for α7 human nAChR . Facinicline hydrochloride (RG3487 hydrochloride) improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride (RG3487 hydrochloride) shows high affinity (antagonist) to 5-HT3Rs with a K i value of 1.2 nM.
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