TCS 21311 (Standard)

Overview

TCS 21311 (Standard) is the analytical standard of TCS 21311 ( HY-108264 ). This product is intended for research and analytical applications. TCS 21311 (NIBR3049) is a potent, highly selective JAK3 inhibitor with an IC 50 of 8 nM, it displays >100-fold selectivity over JAK1 , JAK2 and TYK2 . TCS 21311 (NIBR3049) inhibits PKCα , PKCθ , and GSK3β with IC 50 s of 13, 68, and 3 nM, respectively.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > JAK | Products > Signaling Pathways > PKC | Products > Signaling Pathways > GSK-3 | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-108264R
• CAS No.: 1260181-14-3
• Molecular Formula: C27H25F3N4O4
• Molecular Weight: 526.51
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source