SB-772077B dihydrochloride (Standard)

Overview

SB-772077B dihydrochloride (Standard) is the analytical standard of SB-772077B (dihydrochloride) ( HY-108518 ). This product is intended for research and analytical applications. SB-772077B dihydrochloride is an orally active aminofuran-based Rho K i nase (( ROCK )) inhibitor with IC 50 values of 5.6 nM and 6 nM for ROCK1 and ROCK2 , respectively. SB-772077B dihydrochloride reduces inflammatory cytoK i nes (TNF-α and IL-6 ). SB-772077B dihydrochloride relaxes aortic rings and lowers blood pressure. SB-772077B dihydrochloride can be used in the research of inflammatory diseases.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > ROCK

Product Information

• Catalog No.: HY-108518R
• CAS No.: 607373-46-6
• Molecular Formula: C15H20Cl2N8O2
• Molecular Weight: 415.28
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source