SU16f (Standard) is the analytical standard of SU16f ( HY-108628 ). This product is intended for research and analytical applications. SU16f is a potent and selective PDGFRβ inhibitor with IC 50 s of 10 nM, 140 nM, 2.29 μM for PDGFRβ , VEGF-R2, FGF-R1, respectively. Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration.
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