PF-06465469 (Standard) is the analytical standard of PF-06465469 ( HY-108691 ). This product is intended for research and analytical applications. PF-06465469 is a covalent inhibitor of ITK with an IC 50 of 2 nM. PF-06465469 also inhibits BTK . PF-06465469 inhibits cell migration in response to CXCL12. PF-06465469 decreases PD-1 and LAG-3 expression. PF-06465469 can be used to study leukemia and T-cell lymphoma.
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