VU0650786 (Standard) is the analytical standard of VU0650786 ( HY-108710 ). This product is intended for research and analytical applications. VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC 50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents.
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