S07662 is a human constitutive androstane receptor ( hCAR ) inhibitor with an IC 50 of 0.7 μM. S07662 recruits the corepressor NCoR in cell-based assays and attenuate the expression of CYP2B6 mRNA in human primary hepatocytes induced by phenytoin ( HY-B0448 ) and CITCO ( HY-103244 ).
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Constitutive Androstane Receptor
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