Taminadenant (Standard)

Overview

Taminadenant (Standard) is the analytical standard of Taminadenant ( HY-109139 ). This product is intended for research and analytical applications. Taminadenant (NIR178; PBF509) is a highly potent and orally active adenosine A2A receptor (A2AR) antagonist. Taminadenant can antagonize A2AR agonist-mediated cAMP accumulation and impedance responses with KB values of 72.8 nM and 8.2 nM, respectively. Taminadenant reverses motor impairments in several rat models of movement disorders, including catalepsy, tremor, and hemiparK i nsonism. Taminadenant can also inhibit tumor growth when combined with Spartalizumab ( HY-P9972 ). Taminadenant reactivate the antitumor immune response.

Application

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Product Information

• Catalog No.: HY-109139R
• CAS No.: 1337962-47-6
• Molecular Formula: C10H8BrN7
• Molecular Weight: 306.12
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source