NBUMP is a 5-HT 1 A receptor ligand with a 5-HT 1 A receptor K i of 0.1 nM, α 1 -adrenergic receptor K i of 46 nM, and a 5-HT 1 A receptor-to-α 1 -adrenergic receptor selectivity ratio of 460.NBUMP binds to the 5-HT 1 A receptor with high affinity.NBUMP binds to the α 1 -adrenergic receptor with lower affinity.
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