AZ-11665362 is a CRTh2 ( DP2 ) receptor antagonist with an IC 50 of 2.6 nM. AZ-11665362 shows weak activity against aldose reductase , serotonin transporter , CYP 2C19 , and CYP 2C9 . AZ-11665362 lacks measurable inhibitory activity against COX-1 and COX-2 . AZ-11665362 can be used for the research of asthma, and other inflammatory diseases.
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