Sequoiaflavone

Overview

Sequoiaflavone is a biflavonoid compound with multiple activities. Sequoiaflavone suppresses hepatic CYP1A1/(7-Ethoxycoumarin O-deethylase) ECOD , prevents Aβ 1-42 fibrillization ( IC 50 = 0.29 μM) and disaggregates amyloid fibrils ( EC 50 = 2.04 μM), inhibits Alternaria alternata and inhibits human recombinant PDE5A1 overexpressed in COS-7 cells ( IC 50 = 19.9 μM) to exert NO-independent vasodilation. Sequoiaflavone can be used in Alzheimer's disease, peripheral circulatory disorder, and antifungal research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Fungal Infection | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Neurological Disease | Products > Research Areas > Infection | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > Fungal

Product Information

• Catalog No.: HY-119416
• CAS No.: 21763-71-3
• Molecular Formula: C31H20O10
• Molecular Weight: 552.48
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source