CP-94707 is an HIV-1 reverse transcriptase ( HIV-1 reverse transcriptase) inhibitor, with an IC 50 of 4 μM against wild-type and HIV-1 reverse transcriptase Y181I-Y188L double mutant enzymes , and an IC 50 of 10 μM against HIV-1 reverse transcriptase K103N mutant enzyme. CP-94707 inhibits the initiation of negative-strand DNA synthesis primed by tRNA Lys-3 , as well as the elongation of DNA synthesis mediated by HIV-1 reverse transcriptase. CP-94707 can be used in studies related to HIV infection.
Products | Products > Disease Areas > Infection | Products > Disease Areas > HIV Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Reverse Transcriptase | Products > Signaling Pathways > HIV
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