BLT-3 is an inhibitor of scavenger receptor class B type I ( SR-BI ) that exerts reversible, non-cell-type-specific inhibitory effects on SR-BI -mediated lipid transport. BLT-3 inhibits SR-BI -mediated selective lipid uptake from HDL as well as cholesterol efflux from cells to HDL. BLT-3 enhances the binding of HDL to SR-BI . BLT-3 is applicable to research related to atherosclerosis and coronary heart disease.
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