(rel)-AM-6226

Overview

(rel)-AM-6226 is the relative stereoisomer of AM-6226 ( HY-120493A ). AM-6226 is a potent, orally active full agonist of G protein-coupled receptor 40 ( GPR40 ) with an EC 50 value of 0.12 μM. AM-6226 activates GPR40 receptors on pancreatic β-cells and enteroendocrine L-cells, promotes insulin secretion in a glucose-dependent manner, and increases the release of incretin hormones ( GLP-1 , GIP), thus avoiding the risk of hypoglycemia. AM-6226 can be used in the research of metabolic diseases such as diabetes.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Free Fatty Acid Receptor

Product Information

• Catalog No.: HY-120493
• CAS No.: 1142222-28-3
• Molecular Formula: C32H36F2O4
• Molecular Weight: 522.62
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source