MK-785 is a histidine decarboxylase inhibitor. MK-785 interacts with the cofactor Pyridoxal phosphate ( HY-B1744 ). MK-785 reduces basal and gastrin-stimulated gastric acid secretion. MK-785 decreases the formation of stress ulcers induced by cold stress and restraint stress. MK-785 inhibits gastric histidine decarboxylase activity in brown rats. MK-785 can be used in studies related to stress ulcers.
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