GW694481 is an ApoA1 upregulator with IC 50 values of 2.1 μM for CYP2C9 inhibition and 17.0 μM for CYP3A4 inhibition. GW694481 upregulates ApoA1 expression in human hepatic cells.GW694481 can be used for the research of atherosclerosis.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Chronic Disease and Inflammation | Products > Disease Areas > Atherosclerosis and Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Cytochrome P450
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