MK-3901

Overview

MK-3901 is a selective P2X3 receptor antagonist with an IC 50 of 24 nM. MK-3901 inhibits UGT1A1 (with an IC 50 of 1 μM) and CYP2C9 (with an IC 50 of 5.7 μM). MK-3901 activates PXR . MK-3901 induces hyperbilirubinemia. MK-3901 can be used for the research of inflammatory pain.

Application

Products | Products > Disease Areas > Pain | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > P2X Receptor | Products > Signaling Pathways > UGT | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > Pregnane X Receptor (PXR)

Product Information

• Catalog No.: HY-122163
• CAS No.: 1149750-69-5
• Molecular Formula: C28H24FN5O2
• Molecular Weight: 481.53
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source