TFC-007, a selective hematopoietic prostaglandin D synthase ( H-PGDS ) inhibitor, show high inhibitory activity against H-PGDS enzyme ( IC 50 value of 83 nM). TFC-007 can be used for composing H-PGDS degradation inducer PROTAC (H-PGDS)-1 (TFC-007 binds to H-PGDS, and Pomalidomide binds to cereblon ).
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > PGE synthase | Products > Signaling Pathways > Ligands for Target Protein for PROTAC
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