L505-yne

Overview

L505-yne is an active site-directed γ-secretase inhibitor. L505-yne blocks photoaffinity labeling of PS1-NTF , PS1-CTF , and SPP by clickable GSI photoprobes, binds the γ-secretase complex and inhibits Aβ42 production. L458-BPyne can be used for the research of Alzheimer’s disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > γ-secretase

Product Information

• Catalog No.: HY-123761
• CAS No.: 1374647-07-0
• Molecular Formula: C52H64N4O7
• Molecular Weight: 857.11
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source