H77-77 is a selective MAO-A inhibitor with blood-brain barrier permeability, exhibiting an IC 50 of 7.4 μM against rat MAO-A . H77-77 accumulates via uptake by serotonergic and noradrenergic neurons. H77-77 releases norepinephrine and serotonin from intracellular neuronal storage sites. H77-77 can be used in studies related to neurological disorders.
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