YH18968

Overview

YH18968 is an orally active GPR119 agonist with an EC 50 of 2.8 nM for inducing cAMP accumulation. YH18968 activates GPR119 , elevates intracellular cyclic adenosine monophosphate levels, stimulates glucagon-like peptide-1 secretion from intestinal L cells, and triggers glucose-dependent insulin secretion from pancreatic β cells. YH18968 improves glucose tolerance in normal mice and diet-induced obese mice. YH18968 can be used for the research of type 2 diabetes.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Type 2 Diabetes | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > GPR119

Product Information

• Catalog No.: HY-125646
• CAS No.: 1632498-56-6
• Molecular Formula: C27H28FN9O3
• Molecular Weight: 545.58
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source