MY-1250

Overview

MY-1250 is a histamine release inhibitor. MY-1250 is the major active metabolite of Repirinast ( HY-109544 ). MY-1250 stimulates adenylate cyclase to increase intracellular cyclic adenosine monophosphate levels, reduce intracellular ATP levels, inhibit antigen-induced intracellular calcium store mobilization, and induce phosphorylation of the 78 kDa protein. MY-1250 inhibits antigen- and phospholipase A 2 -induced release of histamine and slow-reacting substance of anaphylaxis from mast cells, lung tissue fragments and basophils. MY-1250 can be used in research related to allergic diseases and bronchial asthma.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lower Respiratory Inflammation | Products > Disease Areas > Respiratory Inflammation | Products > Disease Areas > Allergy | Products > Disease Areas > Asthma | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Histamine Receptor | Products > Signaling Pathways > Adenylate Cyclase | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-129272
• CAS No.: 63768-47-8
• Molecular Formula: C15H11NO5
• Molecular Weight: 285.26
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source