4-Methoxybiphenyl

Overview

4-Methoxybiphenyl is a cytochrome P450 -dependent microsomal monooxygenase system substrate and metabolite precursor. 4-Methoxybiphenyl undergoes O-demethylation to generate 4-hydroxybiphenyl. 4-Methoxybiphenyl undergoes sulphation and glucuronidation conjugation; inhibition of sulphation shifts metabolism toward increased glucuronidation and unconjugated 4-hydroxybiphenyl accumulation. 4-Methoxybiphenyl serves as a model substrate for studying phase II metabolic conjugation pathway balance in rat isolated hepatocytes.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-129565
• CAS No.: 613-37-6
• Molecular Formula: C13H12O
• Molecular Weight: 184.24
• Storage: Store at room temperature 3 years. In solvent -80°C, 2 years , -20°C, 1 year
• Availability: In-stock

Source

Original product source