L-γ-Carboxyglutamic acid

Overview

L-γ-Carboxyglutamic acid (H-Gla-OH) is a mGluR2 antagonist with an IC 50 of 102 μM. L-γ-Carboxyglutamic acid binds to the mGluR2 receptor site via the overlapping extended amino acid conformation of its amino and carboxyl groups with glutamic acid, and its additional acidic group locates in a restricted region, thereby blocking the full activation of the receptor. L-γ-Carboxyglutamic acid can be used for the research of neurological disorders.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mGluR

Product Information

• Catalog No.: HY-131642
• CAS No.: 53861-57-7
• Molecular Formula: C6H9NO6
• Molecular Weight: 191.14
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source