HMR 1031

HMR 1031
  • CAS No.:479203-71-9
  • Formula:C35H41N5O6
  • M.W.:627.74

Overview

HMR 1031 is a very late antigen-4 ( VLA4 , i.e., integrin α4β1 ) inhibitor, with IC 50 values of 0.7 nM and 0.3 nM against VLA-4/VCAM-1 and VLA-4/fibronectin, respectively. HMR 1031 blocks allergen-induced airway responses and airway inflammation in mouse and sheep models. HMR 1031 can be used in asthma-related research.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lower Respiratory Inflammation | Products > Disease Areas > Respiratory Inflammation | Products > Disease Areas > Asthma | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Integrin

Product Information

  • Catalog No.: HY-136692
  • CAS No.: 479203-71-9
  • Molecular Formula: C35H41N5O6
  • Molecular Weight: 627.74
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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