PD151242

Overview

PD151242 is a selective competitive antagonist of the endothelin ET A receptor , with K D values of 0.65 nM, 0.64 nM and 1.92 nM for human, rat and porcine receptors, respectively, and a K D value of 104 μM for the human ET β receptor. When radiolabeled as [ 125 I]-PD151242, PD151242 can be used to visualize and localize renal vascular ET A receptors.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Endothelin Receptor | Products > Signaling Pathways > Radionuclide-Drug Conjugates (RDCs)

Product Information

• Catalog No.: HY-136785
• CAS No.: 155561-67-4
• Molecular Formula: C34H45N5O6
• Molecular Weight: 619.76
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source