(+)-Razpipadon ((+)-PW0464) is a selective D1 dopamine receptor agonist belonging to non-catechol compounds. (+)-Razpipadon activates the G protein pathway, while restricting β-arrestin coupling through the proximity effect of fluoromethyl-TM5, thereby achieving specific regulation of downstream pathways. (+)-Razpipadon can be used in studies related to Parkinson's disease.
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