TH7299

Overview

TH7299 is a TbFolD inhibitor with antiparasitic activity. TH7299 binds the tetrahydrofolate-binding pocket of MTHFD2 , and inhibits MTHFD2L and the dehydrogenase/cyclohydrolase domain of MTHFD1 . TH7299 reduces cancer cells viability, induces apoptosis , DNA damage. TH7299 can be used for the researches of african trypanosomiasis and acute myeloid leukemia.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Trypanosome Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Methylenetetrahydrofolate Dehydrogenase (MTHFD) | Products > Signaling Pathways > Parasite | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-148014
• CAS No.: 1415648-20-2
• Molecular Formula: C17H19N7O7
• Molecular Weight: 433.38
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source