CN-716 dihydrochloride

Overview

CN-716 dihydrochloride is a reversible covalent flavivirus NS2B·NS3 protease inhibitor with antiviral activity. CN-716 dihydrochloride effectively inhibits the replication of dengue virus ( DENV2 ), West Nile virus ( WNV ) and Zika virus ( ZIKV ). The IC 50 values of CN-716 dihydrochloride against the proteases of the above three viruses are 0.066 μM, 0.11 μM and 0.25 μM, respectively, while the K i values against the same proteases are 0.051 μM, 0.082 μM and 0.04 μM, respectively. CN-716 dihydrochloride can be used to study the infection mechanisms of dengue fever, West Nile fever and Zika virus infection .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Disease Areas > Flavivirus Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Flavivirus | Products > Signaling Pathways > Dengue Virus | Products > Signaling Pathways > Virus Protease

Product Information

• Catalog No.: HY-156052
• CAS No.: 2077164-48-6
• Molecular Formula: C22H33BCl2N6O4
• Molecular Weight: 527.25
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source