OPB-171775 (Standard)

Overview

OPB-171775 (Standard) is the analytical standard of OPB-171775 ( HY-162730 ). This product is intended for research and analytical applications. OPB-171775 is an orally active molecular glue. OPB-171775 forms ternary complex with phosphodiesterase 3A (PDE3A) and schlafen family member 12 (SLFN12). OPB-171775 causes SLFN12 RNase-mediated cell death, activates SLFN12 RNase-associated GCN2 signaling pathway. OPB-171775 exhibits significant efficacy against gastrointestinal stromal tumor.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Molecular Glues | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-162730R
• CAS No.: 2131210-15-4
• Molecular Formula: C15H18F2N2O3
• Molecular Weight: 312.31
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source