AM-112

Overview

AM-112 is a β-lactamase ( β-lactamase ) inhibitor and antibacterial agent, with IC 50 values ranging from 0.0002 μg/mL to 0.67 μg/mL against class A, C, and D β-lactamase . By inhibiting PBP2 , the penicillin-binding protein of E. coli , and protecting Ceftazidime ( HY-B0593 ) from enzymatic hydrolysis, AM-112 significantly enhances the antibacterial efficacy of Ceftazidime against Gram-negative bacteria, enterococci, and staphylococci. AM-112 exhibits favorable pharmacokinetic properties and acid-base stability. AM-112 can be used for the research of bacterial infections.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > Beta-lactamase | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Penicillin-binding protein (PBP)

Product Information

• Catalog No.: HY-165460
• CAS No.: 414858-51-8
• Molecular Formula: C14H22N2O5
• Molecular Weight: 298.34
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source