OPC 3911

Overview

OPC 3911 is a highly selective inhibitor of cGMP-inhibited cAMP phosphodiesterase ( cGI-PDE/PDE3 ) and a vasodilator, with an IC 50 of 0.042 μM against rat cGI-PDE. OPC 3911 upregulates the expression of Osteopontin . OPC 3911 mediates vasodilation of arterial smooth muscle, induces vasodilatory responses in isolated rat arteriovenous tissues, and exhibits additive vasodilatory effects with Isoprenaline ( HY-108353 ) and Forskolin ( HY-15371 ). OPC 3911 can be used in studies related to congestive heart failure and insulin resistance.

Application

Products | Products > Disease Areas > Heart Failure | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Heart Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > Osteopontin

Product Information

• Catalog No.: HY-165568
• CAS No.: 76470-87-6
• Molecular Formula: C21H30N2O4
• Molecular Weight: 374.48
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source