DSPE-PEG2000-Mannose

Overview

DSPE-PEG 2000-Mannose is a mannose-containing lipid. DSPE-PEG 2000-Mannose is used to prepare mannose-conjugated Liposome (Man-lipo) for siRNA delivery. Mannose-modified liposomes encapsulating IDO siRNA (Man-lipo-siIDO) preferentially knock down IDO expression in the draining lymph nodes and spleens of melanoma-bearing mice. Man-lipo-siIDO delays the onset time of melanoma and reduces tumor volume.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Melanoma | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Biochemical Assay Reagents | Products > Signaling Pathways > Liposome | Products > Signaling Pathways > Small Interfering RNA (siRNA)

Product Information

• Catalog No.: HY-168374
• CAS No.: 1829524-73-3
• Molecular Formula: C60H110N3O17PS
• Molecular Weight: 2000 (Average)
• Purity: 90.0%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source