BMS-566419

Overview

BMS-566419 is an orally active IMPDH inhibitor with an IC 50 of 91 nM against human IMPDH I and 68 nM against human IMPDH II . BMS-566419 exerts anti-heart transplant rejection and anti-renal fibrosis effects, and inhibits the expression of MCP-1 , TGF-β1 as well as antibody production. BMS-566419 can be used in research on renal fibrosis and organ transplantation.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Lung Fibrosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > IMPDH

Product Information

• Catalog No.: HY-110217
• CAS No.: 566161-24-8
• Molecular Formula: C28H30FN5O2
• Molecular Weight: 487.57
• Purity: 99.68%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source