(R)-PVTX-405

Overview

(R)-PVTX-405 is a IKZF2 molecular glue degrader with a DC 50 of 4.1 nM. (R)-PVTX-405 is the (R)-enantiomer of PVTX-405 ( HY-172930 ). PVTX-405 is an orally active IKZF2 molecular glue degrader that significantly inhibits MC38 tumor growth in mouse tumor xenograft models. (R)-PVTX-405 can be used in cancer-related research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Others | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Molecular Glues | Products > Signaling Pathways > Drug Isomer | Products > Signaling Pathways > IKZF Family

Product Information

• Catalog No.: HY-172930B
• CAS No.: 2991023-13-1
• Molecular Formula: C30H31N5O4
• Molecular Weight: 525.60
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Source

Original product source