MAPK ligand 1 is an apoptosis inducer and Bcl-xL/MAPK ligand that can be used to synthesize the Bcl-xL -targeted PROTAC degrader ( HY-176740 ). MAPK ligand 1 triggers apoptosis through the mitochondrial pathway, MAPK pathway, reduction of mitochondrial membrane potential and elevation of reactive oxygen species levels. MAPK ligand 1 inhibits colony formation and migration of cancer cells, as well as angiogenesis of endothelial cells. MAPK ligand 1 can be used in the research of hepatocellular carcinoma.
Products | Products > Disease Areas > Hepatitis B Virus Related Hepatocellular Carcinoma | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Ligands for Target Protein for PROTAC | Products > Signaling Pathways > Bcl-2 Family
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